Activity-dependent NFATc3 nuclear accumulation in pericytes from cortical parenchymal microvessels

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Activity-dependent NFATc3 nuclear accumulation in pericytes from cortical parenchymal microvessels.

The calcium-dependent transcription factor NFATc3, which is a member of the nuclear factor of activated T cells (NFAT) family of transcription factors, is critical for embryonic vascular development and differentiation. Despite its potential importance, nothing is known about NFATc3 regulation in the brain microcirculation. In the present study, we sought to investigate the role that glutamate,...

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ژورنال

عنوان ژورنال: American Journal of Physiology-Cell Physiology

سال: 2007

ISSN: 0363-6143,1522-1563

DOI: 10.1152/ajpcell.00554.2006